Pharma Specialists

Dissolution

Dissolution Testing of Chewable Tablets

MHRA asks for a dissolution test because a chewable tablet is st…

September 12, 2026

Dissolution

Identifying Discriminatory Dissolution Media Using Artificial Intelligence

AI can help identify the most discriminatory dissolution medium …

September 11, 2026

Dissolution

Dissolution Media Volume Adjustment During a Multipoint Dissolution Test

During a multipoint dissolution test, there are two common appro…

August 08, 2026

Dissolution

Understanding Drug Release Kinetics in Formulation Development

Drug release kinetics is the science of how a drug leaves its do…

November 03, 2025

Biowaiver

Challenging Scenario in Dissolution Justification for Biowaiver

Question Received: I need your input, colleagues. I’m working on…

August 05, 2025

Bootstrap

Comparison of F2 Similarity Factor and Bootstrap Approach

Selection Criteria for Dissolution Profile Evaluation Two princi…

August 05, 2025

Dissolution

Optimizing Dissolution Without Changing the Formula

In generic drug development, achieving the desired dissolution p…

July 11, 2025

Dissolution

Agitation in Dissolution

For immediate-release capsule or tablet formulations, Apparatus …

March 11, 2025

Dissolution

Handling High RSD at Early Time Points in Dissolution Profile Comparison

Dissolution profile comparison is a key aspect of formulation de…

March 09, 2025

Dissolution

Absorptive Dissolution Testing of Supersaturating Systems

It is a crucial method in pharmaceutical research to assess the …

March 08, 2025

Dissolution

Spiked Placebo or Recovery and Specificity of Dissolution Samples

When validating the analysis portion of the dissolution method, …

March 06, 2025

Dissolution

Deaeration in Dissolution

Determining the significance of deaerating the dissolution mediu…

March 03, 2025

Biorelevant

Two-Stage Biorelevant pH Shift Dissolution Test

The two-stage biorelevant pH shift dissolution test is an essent…

March 01, 2025

Dissolution

When Should You Use Baskets in Dissolution?

This may surprise you, but there are seven compendial dissolutio…

January 27, 2025

Dissolution

Global Regulatory Requirements for Multimedia Dissolution Testing

Multimedia Dissolution Testing (MMD) testing refers to evaluatin…

January 10, 2025