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Types of Detector that are Used in Organic Compounds Analysis

In organic compounds analysis, various detectors are employed across instrumental techniques:

1. Mass Spectrometry (MS)

 - Electron Impact (EI) Detector: Common in GC-MS, provides mass spectra for identifying compounds.

 - Chemical Ionization (CI) Detector: Produces molecular ion peaks with less fragmentation.

2. Gas Chromatography (GC)

 - Flame Ionization Detector (FID): Measures hydrocarbons based on ionization in a hydrogen flame.

 - Thermal Conductivity Detector (TCD): Senses changes in thermal conductivity of the carrier gas caused by sample components.

3. Liquid Chromatography (LC)

 - UV-Visible Detector: Absorption of UV or visible light for compounds with suitable chromophores.

 - Fluorescence Detector: Measures emitted light after excitation by UV light, enhancing sensitivity.

4. Infrared Spectroscopy (IR)

 - IR Detector (e.g., MCT): Measures absorption of infrared radiation, providing information about functional groups.

5. Nuclear Magnetic Resonance (NMR)

 - NMR Detector: Records signals from nuclear spins, revealing structural information.

6. Ultraviolet-Visible Spectroscopy (UV-Vis)

 - Photodiode Array (PDA) Detector: Allows simultaneous measurement at multiple wavelengths.

 - Flame Photometric Detector (FPD): Specific for elements like sulfur and phosphorus.

7. Capillary Electrophoresis (CE)

 - UV Absorbance Detector: Monitors absorbance of UV light as compounds pass through the detection point.

These detectors aid in characterizing and quantifying organic compounds, each offering specific advantages depending on the analytical requirements.

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Resource Person: Abu Talha Bin Dil Chowdhury

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