Author: Leon Shargel
Originally Published: 1980
Applied Biopharmaceutics and Pharmacokinetics is a comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics. This book discuss detail about drug product performance and biopharmaceutics, how biopharmaceutics affects drug product performance and define pharmacokinetics and describe how pharmacokinetics is related to pharmacodynamics and drug toxicity.
Table of Contents of Applied Biopharmaceutics and Pharmacokinetics
Chapter 1: Introduction to Biopharmaceutics and Pharmacokinetics
Chapter 2: Mathematical Fundamentals in Pharmacokinetics
Chapter 3: Biostatistics
Chapter 4: One-Compartment Open Model: Intravenous Bolus Administration
Chapter 5: Multicompartment Models: Intravenous Bolus Administration
Chapter 6: Intravenous Infusion
Chapter 7: Drug Elimination, Clearance, and Renal Clearance
Chapter 8: Pharmacokinetics of Oral Absorption
Chapter 9: Multiple-Dosage Regimens
Chapter 10: Nonlinear Pharmacokinetics
Chapter 11: Physiologic Drug Distribution and Protein Binding
Chapter 12: Drug Elimination and Hepatic Clearance
Chapter 13: Pharmacogenetics and Drug Metabolism
Chapter 14: Physiologic Factors Related to Drug Absorption
Chapter 15: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance
Chapter 16: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence
Chapter 17: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence
Chapter 18: Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy
Chapter 19: Modified-Release Drug Products and Drug Devices
Chapter 20: Targeted Drug Delivery Systems and Biotechnological Products
Chapter 21: Relationship Between Pharmacokinetics and Pharmacodynamics
Chapter 22: Application of Pharmacokinetics to Clinical Situations
Chapter 23: Application of Pharmacokinetics to Specific Populations: Geriatric, Obese, and Pediatric Patients
Chapter 24: Dose Adjustment in Renal and Hepatic Disease
Chapter 25: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental Analysis
Appendix A: Applications of Software Packages in Pharmacokinetics
Appendix B: Glossary
A very informative book of biopharmaceutics
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