51. What ingredients are necessary for wet granulation tablet manufacturing?

  1. Binder
  2. Granulating fluid
  3. Diluent
  4. All of them

Right answer is (4)

52. What if the following is least likely an effect of wet granulation for manufactured tablets?

  1. Increase tablet hardness
  2. More disintegration time
  3. Better content uniformity
  4. Increse tablet friability
Right answer is (4)


53. When do we use wet granulation?

  1. Moisture sensitive API
  2. Least complex way
  3. Poor flowability
  4. All of them
Right answer is (3)

54. How to determine end point in wet granulation?

  1. Impeller torque measurement
  2. Power consumption measurement
  3. Voltage
  4. Chopper Speed
Right answer is (1) & (2)

55. How much water to use in a lactose mcc wet granulation?

  1. 5-10%
  2. 15-25%
  3. 40-50%
  4. 60-80%
Right answer is (2)

56. Why is wet granulation good for toxic drugs?

  1. Less dust produce
  2. Better content uniformity
  3. None of them
  4. All of them
Right answer is (4)

57. How to choose between wet and dry granulation?

  1. Particle size distribution
  2. Powder flow
  3. Hygroscopicity
  4. All of them
Right answer is (4)

58. Why use wet granulation?

  1. To improve granules flowability
  2. To get better content uniformity
  3. To improve tabletmechanical strength
  4. All of them
Right answer is (4)

59. How to prepare starch paste for wet granulation?

  1. Starch + Cold water
  2. Starch + Hot water
  3. Starch slurry + Starch + Hot water
  4. None of them
Right answer is (3)

60. What ingredients are necessary for direct compression tablet manufacturing?

  1. Desired particle size
  2. Proper flowability
  3. Required binding property
  4. All of them
Right answer is (3)

61. Which of the following pharmaceutical lubricant is water soluble?

  1. Magnesium Stearate
  2. Steraic acid
  3. Sodium Stearyl Fumarate
  4. Talc
Right answer is (3)

62. Why pharmaceutical lubrication time is not more than 3 to 5 minutes?

  1. Improper mixing
  2. Retarded dissolution
  3. Decrese disintegration time
  4. Increse Friability
Right answer is (2)

63. Which percentage of Magnesium stearate commonly used in pharmaceutical formulation?

  1. 0.25% to 2.5%
  2. 2.5% to 5.0%
  3. 5.0% to 6.0%
  4. All of them
Right answer is (1)

64. Increasing Colloidal Silica in pharmaceutical formulation may increase _____?

  1. Hardness
  2. Dissolution
  3. Friability
  4. None of them
Right answer is (1)

65. What is magnesium stearate used for?

  1. Disintegrant
  2. Lubricant
  3. Binder
  4. Dissolution enhancer
Right answer is (2)

66. What does magnesium stearate do during over mixing?

  1. Forming films on granules
  2. Increasing dissolution rate
  3. Decreasing friability
  4. Increasing hardness
Right answer is (1)

67. What is colloidal anhydrous silica used for?

  1. Glidant
  2. Disintegrant
  3. Dissolution enhancer
  4. Matrix forming agent
Right answer is (1)

68. Why methyl paraben and propyl paraben are used in combination?

  1. It's show antagonistic effect
  2. It's show synergistic effect
  3. There is no special effect
  4. None of them
Right answer is (2)

69. How to dissolve methyl paraben in water?

  1. Stirring at normal water
  2. Stirring at cold water
  3. Stirring at hot water
  4. All of them
Right answer is (3)

70. At which pH methyl paraben and propyl paraben are effective?

  1. 1.0 to 2.0
  2. 2.0 to 3.0
  3. 3.0 to 5.0
  4. 4.0 to 8.0
Right answer is (4)

71. What is the difference between sodium benzoate and methyl paraben as preservatives?

  1. Methyl paraben active at a lower pH than Sodium benzoate
  2. Sodium benzoate active at a lower pH than Methyl paraben 
  3. Sodim benzoate easy to dissolve in water than Methyl Paraben
  4. Both (2) & (3)
Right answer is (4)

72. What is methyl paraben used for in making drug products?

  1. Preservative
  2. Diluent
  3. Binder
  4. Lubricant
Right answer is (1)

73. What is povidone-iodine used for?

  1. To prevent infections
  2. As a binder solution
  3. As a color solution
  4. All of them
Right answer is (1)

74.What is povidone used for in wet granulation?

  1. Diluent
  2. Binder
  3. Lubricant
  4. Glidant
Right answer is (2)

75. What are the pharmaceutical excipients commonly used in antacids?

  1. Magnesium hydroxide
  2. Aluminum hydroxide
  3. Sodium bicarbonate
  4. All of them
Right answer is (4)


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