51. What ingredients are necessary for wet granulation tablet manufacturing?
- Binder
- Granulating fluid
- Diluent
- All of them
Right answer is (4)
52. What if the following is least likely an effect of wet granulation for manufactured tablets?
- Increase tablet hardness
- More disintegration time
- Better content uniformity
- Increse tablet friability
Right answer is (4)
53. When do we use wet granulation?
- Moisture sensitive API
- Least complex way
- Poor flowability
- All of them
Right answer is (3)
54. How to determine end point in wet granulation?
- Impeller torque measurement
- Power consumption measurement
- Voltage
- Chopper Speed
55. How much water to use in a lactose mcc wet granulation?
- 5-10%
- 15-25%
- 40-50%
- 60-80%
Right answer is (2)
56. Why is wet granulation good for toxic drugs?
- Less dust produce
- Better content uniformity
- None of them
- All of them
Right answer is (4)
57. How to choose between wet and dry granulation?
- Particle size distribution
- Powder flow
- Hygroscopicity
- All of them
Right answer is (4)
58. Why use wet granulation?
- To improve granules flowability
- To get better content uniformity
- To improve tabletmechanical strength
- All of them
Right answer is (4)
59. How to prepare starch paste for wet granulation?
- Starch + Cold water
- Starch + Hot water
- Starch slurry + Starch + Hot water
- None of them
Right answer is (3)
60. What ingredients are necessary for direct compression tablet manufacturing?
- Desired particle size
- Proper flowability
- Required binding property
- All of them
Right answer is (3)
61. Which of the following pharmaceutical lubricant is water soluble?
- Magnesium Stearate
- Steraic acid
- Sodium Stearyl Fumarate
- Talc
Right answer is (3)
62. Why pharmaceutical lubrication time is not more than 3 to 5 minutes?
- Improper mixing
- Retarded dissolution
- Decrese disintegration time
- Increse Friability
Right answer is (2)
63. Which percentage of Magnesium stearate commonly used in pharmaceutical formulation?
- 0.25% to 2.5%
- 2.5% to 5.0%
- 5.0% to 6.0%
- All of them
Right answer is (1)
64. Increasing Colloidal Silica in pharmaceutical formulation may increase _____?
- Hardness
- Dissolution
- Friability
- None of them
Right answer is (1)
65. What is magnesium stearate used for?
- Disintegrant
- Lubricant
- Binder
- Dissolution enhancer
Right answer is (2)
66. What does magnesium stearate do during over mixing?
- Forming films on granules
- Increasing dissolution rate
- Decreasing friability
- Increasing hardness
Right answer is (1)
67. What is colloidal anhydrous silica used for?
- Glidant
- Disintegrant
- Dissolution enhancer
- Matrix forming agent
Right answer is (1)
68. Why methyl paraben and propyl paraben are used in combination?
- It's show antagonistic effect
- It's show synergistic effect
- There is no special effect
- None of them
Right answer is (2)
69. How to dissolve methyl paraben in water?
- Stirring at normal water
- Stirring at cold water
- Stirring at hot water
- All of them
Right answer is (3)
70. At which pH methyl paraben and propyl paraben are effective?
- 1.0 to 2.0
- 2.0 to 3.0
- 3.0 to 5.0
- 4.0 to 8.0
Right answer is (4)
71. What is the difference between sodium benzoate and methyl paraben as preservatives?
- Methyl paraben active at a lower pH than Sodium benzoate
- Sodium benzoate active at a lower pH than Methyl paraben
- Sodim benzoate easy to dissolve in water than Methyl Paraben
- Both (2) & (3)
Right answer is (4)
72. What is methyl paraben used for in making drug products?
- Preservative
- Diluent
- Binder
- Lubricant
Right answer is (1)
73. What is povidone-iodine used for?
- To prevent infections
- As a binder solution
- As a color solution
- All of them
Right answer is (1)
74.What is povidone used for in wet granulation?
- Diluent
- Binder
- Lubricant
- Glidant
Right answer is (2)
75. What are the pharmaceutical excipients commonly used in antacids?
- Magnesium hydroxide
- Aluminum hydroxide
- Sodium bicarbonate
- All of them
Right answer is (4)
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