MCQs in Clinical Pharmacy (Part III)

 

A List of Clinical Pharmacy MCQs with Answer

1. The comparison of bioavailability between two dosage forms is refereed as____________.

1. Bioavailability
2. Biopharmaceutics
3. Biological
4. Bioequivalence

Right answer is (4)

2. The highest serum drug concentration following a single dose or at a steady state within a dosing interval is called -

1. Lead
2. Peak
3. Poison
4. Mechanisms

Right answer is (2)

3. Why should care be taken when prescribing warfarin and amiodarone in combination?

1. Amiodarone and warfarin both have an anticoagulant effect.
2. Amiodarone may reverse the anticoagulant effect of warfarin.
3. Amiodarone may increase the anticoagulant effect of warfarin.
4. Warfarin may reverse the antiarrhythmic effect of amiodarone.

Right answer is (3)

4. The substantial degradation of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches the systemic circulation -

1. First-pass metabolism
2. Disposition
3. Antagonist
4. Hydrophilic

Right answer is (1)

5. According to ICH GCP the investigator "should be qualified by -

1. Training and experience
2. Education, training and experience
3. Education and experience
4. Education and training

Right answer is (2)

6. Pharmaceutical equivalent that produce the same effects in patients -

1. Therapeutic equivalent
2. Therapeutic window
3. Minimum effective concentration (MEC)
4. Minimum toxic concentration (MTC)

Right answer is (1)

7. How are prescription medicines different from OTC ones?

1. They contain much smaller amounts of active ingredients
2. They don't contain dyes or preservatives
3. They're unsafe for use without medical supervision
4. They can be toxic

Right answer is (3)

8. Which of the following drug is implicated in the causation of osteomalacia of the bone?

1. Steroid
2. Estrogen
3. Heparin
4. Phenytoin

Right answer is (4)

9. Which of the following drug can result of cyanide poisoning?

1. Amyl nitrite
2. Hydroxycobalamine
3. Sodium nitroprusside
4. Sodium thiosulphate

Right answer is (3)

10. According to the principles of ICH GCP, what is the most important consideration when conducting a clinical trial?

1. Data accuracy
2. Protection of trial subjects
3. Process adherence
4. Statistical quality checks

Right answer is (2)

11. How many people will be selected for phase II trial?

1. The whole market will be under surveillance
2. 500-3000 people
3. 100-300 people
4. 20-50 people

Right answer is (3)

12. Which of the following is a valid therapeutic use of interaction?

1. Use of Probenecid with Penicillin
2. Giving Aspirin with warfarin
3. Instructing patient to take levofloxacin with milk or antacid
4. Treatment of depression of MAO Inhibitor and Citalopram

Right answer is (1)

13. Which of the following antihypertensive agents should be avoided in the elderly patients?

1. Amlodipine
2. Atenolol
3. Benazepril
4. Methyldopa

Right answer is (4)

14. Which of the following medication is safe to use in the third trimester of pregnancy?

1. Acetaminophen
2. Warfarin
3. Aspirin
4. Oxycodone

Right answer is (1)

15. ______________ of clinical trial involves first time human trial in a small number of patients.

1. Phase I
2. Phase II
3. Phase III
4. Phase IV

Right answer is (1)

16. Cimetidine interacts with more drugs than ranitidine because -

1. It is subjected to greater first pass metabolism
2. It is a more potent enzyme inducer
3. It is a more potent enzyme inhibitor
4. It has better oral absorption

Right answer is (3)

17. Who is person responsible for the conduct of the clinical trial at a trial site?

1. Clinical Research Coordinator
2. Monitor
3. Investigator
4. Sponsor

Right answer is (3)

18. Which of the following terms does not describe an Adverse Drug Reaction?

1. Idiosyncrasy
2. Anaphylaxis
3. Teratogenic effect
4. Placebo effect

Right answer is (4)

19. Idiosyncrasy is_______________.

1. Type A ADRs
2. Type B ADRs
3. Type C ADRs
4. Type D ADRs

Right answer is (2)

20. Which of the following drug is not needed to be TDM?

1. Carbamazepine
2. Penicillin
3. Digoxin
4. Gentamicin

Right answer is (2)

21. Gary baby syndrome occur in new born with -

1. Tetracycline
2. Chloramphenicol
3. Penicillin
4. Erythromycin

Right answer is (2)

22. Absorption of Griseofulvin increases with -------------- diet.

1. Carbohydrate
2. Fatty
3. Protein
4. Vitamin

Right answer is (2)

23. When tetracycline is given with antacids the absorption of tetracycline -

1. Increases
2. Decreases
3. Minimally altered
4. Not altered at all

Right answer is (2)

24. Pharmacovigilance is done for monitoring of -

1. Drug price
2. Unethical practices
3. Drug safety
4. Pharmacy students

Right answer is (3)

25. GCP are seen in all of the following except -

1. Phase I trial
2. Phase II trial
3. Preclinical trials
4. Phase IV trial

Right answer is (3)

26. What is the maximum total dose of Meclizine per day?

1. 50 mg
2. 80 mg
3. 100 mg
4. 120 mg

Right answer is (3)

27. If Serum Creatinine value is given in umol/L instead of mg/dL by the Lab, then the value of Serum Creatinine should be divided by what for calculating CrCl by the Cockcroft-Gault equation?

1. 88.2
2. 88.4
3. 88.6
4. 88.8

Right answer is (2)

28. What is the dose of Jardiance (Empagliflozin) for Hyperglycemia and for Heart Failure?

1. 10-25 mg
2. 15-30 mg
3. 20-45 mg
4. 30-50 mg

Right answer is (1)

29. Renal dose dose adjustments of Apixaban (Eliquis) for AFIB is based on 3 things of the patient. What are they?

• Weight, age & serum creatinine
• Weight, age & blood glucose level
• Weight, serum creatinine & blood glucose level
• Weight, age and ESR

Right answer is (1)

Note: If patients meet 2 out of 3 of following criteria you would renally dose adjust: Weight <60kg, Age >80 & SCr >1.5.

30. How many shots of Hepatitis B vaccine a child gets?

1. 2
2. 3
3. 4
4. 5

Right answer is (2)

Read also: MCQs in Clinical Pharmacy (Part I)

Tags in: Online Pharma Quiz, Hospital Pharmacy MCQ, Clinical Pharmacy MCQ Online.