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Clinical Pharmacist Interview Questions and Answers

A List of Interview Questions and Answers for Hospital Pharmacist and Clinical Pharmacist

What is Clinical pharmacy?

Clinical pharmacy is a branch of pharmacy that discuss about patient care with the use of safe medications to optimize the health outcomes of patients. This includes promoting wellness and preventing disease.

What are the 7 patients rights to be confirmed by a hospital/clinical pharmacist?

7 patients rights: 

  • Right Medication, 
  • Right Patient, 
  • Right Dose, 
  • Right Time, 
  • Right Route, 
  • Right Indication, 
  • Right Documentation.

What are the major job responsibilities of a clinical pharmacist?

  • Therapeutic Drug Monitoring (TDM)
  • Rational drug use
  • Observing medication outcomes and comparative effectiveness
  • Monitoring pharmacokinetics and pharmacodynamics
  • Transitions-of-care Services
  • Providing evidence-based information and advice about the safe and effective use of medications.

What do you mean by rational drug use?

Rational drug use means to guarantee the patient the proper use of the best drugs available.

Which PK/PD parameters to be monitored during patient care?

  • Drug Clearance
  • Drug Elimination
  • Volume of Distribution
  • The Half-Life
  • Dosing Variations
  • Oral Availability
  • Pharmacodynamics
  • Pharmacogenetics
  • Saturable Drug Metabolism
  • Protein Binding
  • PH and Pharmacokinetics
  • Dosing and Age
  • Drugs in Pregnancy
  • Drug Interactions
  • Drug Transport

What do you mean by pharmacovigilance?

Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine-related problem.

What are the types of pharmacovigilance?

  • Passive surveillance.
  • Active surveillance.
  • Cohort event monitoring.
  • Targeted Clinical Investigations

What are the four main components of pharmacovigilance?

  • Adverse Event Case Management including expedited reporting; 
  • Aggregate Reporting; 
  • Signal Intelligence; and 
  • Risk Management

What is a dosing regimen?

Dosage regimen includes the frequency of administration, the dose per a single administration, the time interval between administrations, duration of treatments, and how a medicine is to be taken.

What do you mean by initial loading dose and maintenance dose?

Initial loading dose: In some conditions certain drugs are given in large doses in the beginning to obtain an effective blood level rapidly, this is known as initial loading dose.

Maintenance dose: After achieving a desired blood level by initial loading dose, smaller quantity of drug is then required to maintain the blood level, this is known as maintenance dose.

How to calculate loading dose?

Loading dose = (Vd*TC)/F

  • Vd = Volume of Distribution
  • TC = Target Concentration
  • F = Fraction of Absorption (aka Bioavailability)

How to calculate Volume of Distribution (Vd)?

Vd = (F x Loading Dose)/TC

How to calculate maintenance dose and clearance?

  • Maintenance dose = (CL*TC)/F x Dosing Interval
  • CL (Clearance) = Maintenance Dose/(Dosing Interval x C)

Which patient information to be collected?

  • Demographics
  • Current problems
  • Past medical history
  • Current medication
  • Social habits
  • Relevant laboratory data
  • Subsequent modifications of therapy plan

What do you mean by Uremia?

It is characterized by impaired glomerular filtration and accumulation of fluid and protein metabolism. In both the cases the half life of the drug are increased as a consequences drug accumulation and toxicity increases.  

More related questions

  • What is the difference between hospital pharmacist and clinical pharmacist?
  • What made you choose a career as a clinical pharmacist?
  • What is your experience of working in a clinical setting?
  • How do you keep up with pharmaceutical trends?
  • How do you advise patients on drug interactions?
  • How do you manage disputes between pharmacy technicians?
  • What are 3 of your weaknesses?
  • What are 3 of your strengths?


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